The paper, after introducing an overview of Aerospace Engineering courses organization, describes the Design-Lab teaching activity offered to the third year undergraduate students and reports a critical analysis of six years of activity, that involved till now 478 students. During the presentation will be illustrated the encountered difficulties, in particular related to the large number of participating students, and on the other hand the positive feedbacks received from the students. Two examples of Design-Lab will be reported and finally an overview of future implementation of these multidisciplinary activities into the reshaped Aerospace Engineering course organization, for a better CDIO implementation purpose, will be provided.